Synthesis, characterization, and biological properties of composites of hydroxyapatite and hexagonal boron nitride

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dc.authoridEkren, Nazmi/0000-0003-3530-9262|Sahin, Yesim Muge/0000-0003-2119-1216|Unal, Semra/0000-0001-9084-9611|Gunduz, Oguzhan/0000-0002-4926-6489|Gunduz, Oguzhan/0000-0002-9427-7574|Kilic, Osman/0000-0002-4560-5527
dc.authorwosidSengil, Ahmet Zeki/AAG-6141-2019
dc.authorwosidEkren, Nazmi/AAA-3546-2019
dc.authorwosidSahin, Yesim Muge/HDM-3819-2022
dc.authorwosidSahin, Yeşsim Muge/AAQ-7447-2020
dc.authorwosidUnal, Semra/HKN-2430-2023
dc.authorwosidGunduz, Oguzhan/AAA-3212-2019
dc.authorwosidkilic, osman/HJP-8488-2023
dc.contributor.authorUnal, Semra
dc.contributor.authorEkren, Nazmi
dc.contributor.authorSengil, Ahmet Z.
dc.contributor.authorOktar, Faik N.
dc.contributor.authorIrmak, Ster
dc.contributor.authorOral, Ozlem
dc.contributor.authorSahin, Yesim M.
dc.date.accessioned2024-07-18T20:40:02Z
dc.date.available2024-07-18T20:40:02Z
dc.date.issued2018
dc.departmentİstanbul Bilgi Üniversitesien_US
dc.description.abstractHydroxyapatite (HA), obtained from bovine bones, was successfully reinforced with hexagonal boron nitrite (h-BN). h-BN/HA composites, with BN content up to 1.5 wt %, were sintered at various temperatures between 1000 and 1300 degrees C, in air. Well-sintered samples were obtained after sintering at 1200 and 1300 degrees C. The presence of h-BN contributed to dense, fine, and well-crystallized microstructure. The results of X-ray diffraction analysis and FT-IR spectroscopy showed that the produced composites comprised biphasic beta-TCP/HCA (HCA: carbonate partially substituted HA). High values of mechanical properties were achieved, namely compression strength 155 MPa for the sample 0.5% h-BN/HA and Vickers microhardness of 716 HV for the samples 1.5% h-BN/HA, both sintered at 1300 degrees C. U2OS human bone osteosarcoma proliferation and cell viability showed no adverse effect in the presence of h-BN/HA, suggesting the potential use of the produced materials as safe biomaterials in bone tissue engineering. (C) 2017 Wiley Periodicals, Inc.en_US
dc.identifier.doi10.1002/jbm.b.34046
dc.identifier.endpage2392en_US
dc.identifier.issn1552-4973
dc.identifier.issn1552-4981
dc.identifier.issue6en_US
dc.identifier.pmid29168913en_US
dc.identifier.scopus2-s2.0-85034827467en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage2384en_US
dc.identifier.urihttps://doi.org/10.1002/jbm.b.34046
dc.identifier.urihttps://hdl.handle.net/11411/6939
dc.identifier.volume106en_US
dc.identifier.wosWOS:000442988800030en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofJournal of Biomedical Materials Research Part B-Applied Biomaterialsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCompositesen_US
dc.subjectHydroxyapatiteen_US
dc.subjectBovine Boneen_US
dc.subjectHexagonal Boron Nitrideen_US
dc.subjectBioceramicen_US
dc.subjectMechanical-Propertiesen_US
dc.subjectSintering Temperatureen_US
dc.subjectApatiteen_US
dc.subjectNanoparticlesen_US
dc.subjectNanotubesen_US
dc.subjectBhaen_US
dc.titleSynthesis, characterization, and biological properties of composites of hydroxyapatite and hexagonal boron nitride
dc.typeArticle

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